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Drug Safety Testing: Increasing Awareness and Saving Lives

o-called “drug safety testing” is users willingly sending up a sample of their drugs for testing to determine what they contain, including any impur…

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Every summer, alcohol and other drugs are consumed at music festivals all around the world. While the majority of people like this activity, both legal and illegal narcotics may be hazardous. A drug harm reduction approach, on the other hand, may make your music event safer for everyone.

Setting clear expectations for your participants, offering information and tools to help them stay safe, and being transparent in your approach will all help to lessen the risk of harm.

I volunteered at a music festival over the summer before starting to work with organizations that help people to recover. The majority of the volunteers saw it as a means to witness their favorite artists without having to pay a high-ticket price. We wandered about the campgrounds soaking up the ambiance and engaging with nice festival-goers for most of the job, which was simple and delightful. However, there were times when it took on a more frightening tone. One particular moment will remain etched in my consciousness for the rest of my life. We were directed to stroll in lines across the campgrounds on our last shift, the morning after the final night of music, opening abandoned tents and looking inside. We were supposed to look for corpses.

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Drug-related deaths are unfortunately becoming an unavoidable reality at music festivals.

Users will be able to make more informed judgments if drugs are no longer an unspoken reality of music events.

The little knowledge these people have about the drugs usually comes from their dealer or their friends. As a result, people are consuming chemicals that are significantly more harmful than they are thought to be. What festival-goers are offered as MDMA, for example, might contain anything from concrete and insecticide to, more dangerously, PMA—a very poisonous version of ecstasy that takes longer to kick-off, causing users to drink more in the delusion that it isn’t working. Even if the medicine is exactly what it says it is, users who are ignorant of its strength are at risk of taking lethal doses.

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Fortunately, as a growing number of festivals implement on-site drug testing for guests, such as MDMA test kits, the incidence of drug-related disasters appears to be on the decline.

Knowing what’s in a drug and how powerful it is can help you avoid overdosing, poisoning, or long-term harm. So-called “drug safety testing” is users willingly sending up a sample of their drugs for testing to determine what they contain, including any impurities and strength, without fear of being arrested. People are also offered tips on how to reduce the risks associated with drug use. Testing can be done on the spot, or results can be obtained within a few days.

But where is the drug safety testing taking place?

A rising number of nations, including Austria, Canada, Colombia, Mexico, the Netherlands, Switzerland, the United States, and the United Kingdom, are conducting drug safety testing.

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This briefing focuses on testing using advanced analytical equipment, rather than DIY kits that can’t detect many toxins, or on strength.

• In the United Kingdom, onsite drug testing (known as Multi-Agency Safety Testing – MAST) with findings in half an hour was trialed at two events in 2016 and is now being expanded. Samples can also be mailed to WEDINOS1, a drug testing laboratory supported by the Welsh Government, with findings available online in 72 hours, revealing the key elements but not the strength.

• Clubbers in Swiss towns such as Bern and Zurich send off drugs for testing in the middle of the week and receive the findings by Friday. They contact a drug counselor, who offers harm reduction counseling and informs them about the contents and potency of their sample.

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• Drug testing has long been practiced in the Netherlands, particularly in city areas, with results generally arriving within 1-2 days.

• The ‘Checkit’3 initiative in Austria includes a mobile facility that conducts on-site testing at music festivals throughout the year.

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What role does the test play in risk reduction?

Drugs of high and varied potency, as well as pollutants, are major contributors to drug-related deaths. Testing so individuals know what they’re taking, as well as specific professional advice on the best method to take (or not consume) them, decreases the danger of overdose or poisoning. It also allows for the delivery of tailored health advice to “hidden populations” who aren’t using drug services, as well as the monitoring of drug composition and trends. Medical and emergency services can be notified, and public warnings can be made if abnormally potent, tainted, or mis-sold medications are discovered.

Given the ambiguity surrounding the composition of illicit substances, drug safety testing helps all drug users, including those at festivals, nightclubs, and the general drug-using public. For example, in Copenhagen’s new drug consumption area, drug safety testing will be available for heroin users to identify impurities and varied strength, therefore reducing damage, including fatal overdoses.

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Health

IIT-K and BFI collaborate to drive healthcare innovation in India

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IIT-K and BFI forge partnership to accelerate healthcare innovation in India

Kanpur, April 17 (IANS) – The Indian Institute of Technology Kanpur (IIT-K) has entered into a strategic partnership with Blockchain For Impact (BFI) to drive advancements in healthcare in India. Under the BFI-Biome Virtual Network Programme, this collaboration aims to nurture innovations in the healthcare sector.

As part of the partnership, BFI will support IIT Kanpur in promoting entrepreneurial initiatives through the Startup Incubation & Innovation Centre (SIIC). A Memorandum of Understanding (MoU) was signed at IIT Kanpur by Prof. Kantesh Balani, Dean of Resources and Alumni (DoRA), IIT Kanpur; and Dr. Gaurav Singh, CEO BFI.

BFI has committed to allocating over $150,000 across three years to develop programmes tailored to healthcare-focused startups at IIT Kanpur’s SIIC. This collaboration harnesses IIT Kanpur’s expertise in fostering entrepreneurship and BFI’s dedication to advancing biomedical research.

Prof. Kantesh Balani, DoRA, IIT Kanpur, expressed his optimism about the partnership, stating, “This MoU will help us share knowledge, support startups effectively, and improve our capacity-building efforts.” Dr. Gaurav Singh, CEO of BFI, highlighted the inspiring work of IIT Kanpur incubatees in healthcare innovation and the alignment of missions to accelerate impactful solutions in biomedical research.

This partnership signifies a significant step towards advancing healthcare innovation in India by leveraging expertise and resources. The collaboration between IITK and BFI holds promise for improving public health and ensuring equitable healthcare access for all.

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Doctors are hopeful that gene therapy could be a breakthrough for haemophilia, a blood disorder

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Gene therapy holds promise for blood disorder haemophilia: Doctors

On World Haemophilia Day, doctors highlighted the potential of gene therapy in treating haemophilia, a hereditary blood disorder. Haemophilia is caused by missing or defective clotting factors and raises the risk of severe bleeding and joint damage. Genetic counselling and screening are crucial for affected individuals. India has a high number of haemophilia cases, but many go undiagnosed due to lack of screening capabilities.

Gene therapy offers a promising approach to treating haemophilia by delivering functional genes to correct the genetic defect responsible for deficient clotting factor production. Recent clinical trials show positive outcomes, including the use of lentiviral vectors at CMC Vellore. While current treatment involves factor VIII infusions, gene therapy may offer a cure for haemophilia, especially in low and middle-income countries.

According to Anoop P, Sr. Consultant – Haematology at Aster RV Hospital, “Gene therapy is a potentially curative treatment for haemophilia.” It allows for editing the faulty gene of a baby inside the uterus, known to be born with haemophilia due to a family history. Ongoing research on gene therapy shows promising results, indicating a potential paradigm shift in the management and cure of haemophilia.

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The Connection Between Daytime Sleep and Increased Risk of Dementia

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How daytime sleep can raise dementia risk

New Delhi, April 17 (IANS) Compensating for lack of sleep during the daytime may not be as effective as previously thought, warned Dr. Sudhir Kumar, a neurologist based in Hyderabad. According to Dr. Sudhir, daytime sleep is not in sync with the body’s natural clock and can increase the risk of dementia and other psychiatric disorders.

Dr. Sudhir, from Indraprastha Apollo Hospitals, highlighted in a post on X.com that daytime sleep is lighter and does not fulfill the body’s sleep requirements. He explained, “This fact is supported by numerous studies of night shift workers, who are predisposed to stress, obesity, cognitive deficits, and an elevated risk of neurodegenerative diseases.”

The neurologist pointed out that the glymphatic system, responsible for clearing the brain of protein waste products, is most active during sleep. Therefore, when there is a lack of sleep, the glymphatic system may fail, increasing the risk of dementia. Dr. Sudhir stated, “Glymphatic failure is the common pathway of dementia, leading to the accumulation of abnormal proteins in the brain.”

Factors such as poor sleep quality, age, sedentary lifestyle, cardiovascular diseases, obesity, sleep apnoea, circadian misalignment, substance abuse, and depression can also suppress or result in the failure of the glymphatic system. Dr. Sudhir emphasized, “Good sleepers tend to live longer, weigh less, have a reduced incidence of psychiatric disorders, and maintain cognitive function for longer periods.”

In conclusion, Dr. Sudhir advised that consistently sleeping well at night can lead to better cognitive function and decrease the risk of dementia and psychiatric disorders. It is essential to prioritize quality sleep to maintain overall brain health and reduce the risk of neurodegenerative diseases.

–IANS
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