Health

Leaky blood vessels behind Long Covid-linked brain fog, says study

In a major discovery, a team of scientists from Trinity College Dublin discovered disruption to the blood vessels in the brains of patients suffering from Long Covid and ‘brain fog’. The study showed that blood vessel “leakiness” distinguished those patients with brain fog and cognitive decline compared to patients suffering from Long Covid but not with brain fog. The findings were reported in the journal Nature Neuroscience.

Prof. Matthew Campbell, Professor in Genetics and Head of Genetics at Trinity, stated, “For the first time, we have been able to show that leaky blood vessels in the human brain, in tandem with a hyperactive immune system may be the key drivers of brain fog associated with Long Covid. This is critically important, as understanding the underlying cause of these conditions will allow us to develop targeted therapies for patients in the future.” The findings will likely change the landscape of how post-viral neurological conditions are understood and treated.

The discovery may change the understanding of post-viral syndromes, as they might drive blood vessel leakage in the brain. Long Covid has become a major public health issue since the outbreak of the pandemic in 2020 and affects up to 10 per cent of patients infected with the SARS-CoV2 virus. Just under 50 per cent of patients report lingering neurological effects, including cognitive decline, fatigue, and brain fog.

This novel discovery is a significant step towards understanding and developing targeted therapies for patients suffering from Long Covid and its associated neurological symptoms. The team’s findings will likely revolutionize the understanding and treatment of post-viral neurological conditions, providing hope for the future treatment of patients suffering from these symptoms.

IANS

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