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What does CBD salve do for the body and brain?

Cannabis has long been used for medical treatments. The many effects that cannabis plant extracts have had on the treatment of brain diseases, esp…

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What does CBD salve do for the body and brain?

Cannabis has long been used for medical treatments. The many effects that cannabis plant extracts have had on the treatment of brain diseases, especially in the last decade, are significant. 

The main ingredient in marijuana is tetrahydrocannabinol (THC), which is a specific substance behind drug abuse. The second major ingredient is cannabidiol (CBD). CBD is not a psychoactive substance and its effects on brain circuits are very different from those of THC. 

Cannabinoids (cannabis extract) act by binding to specific receptors in brain tissue. These receptors are known as cannabinoid receptors. These receptors directly affect the cell function in which they are located, the psychological effects of marijuana use begin quickly. Such receptors are mainly present in the brain in the hippocampus and cerebellum.

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Psychedelic cannabinoids, such as THC, cause euphoria, increased sensory perception, increased heart rate, decreased pain stimuli, and difficulty concentrating on specific tasks

Research has shown that cannabidiol (CBD) differs from THC in that it has an effect on the human brain. CBD, as mentioned, is not a psychedelic, so it prevents the brain from moving toward emotions and altered realities.

Also Read: Which Countries are Next for Medical Cannabis Legalization?

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CBD can even block the psychoactive effects of THC and eliminate the “excessive” effect by giving it a highly controlled, therapeutic effect. Due to its antipsychotic effects, this compound has been used for many medicinal purposes 

Many studies in laboratories around the world, along with controlled clinical trials, have proven that CBD can be a tolerable, safe, and effective drug for antipsychotic purposes.

The primary mechanism by which CBD can be used to prevent traumatic brain injury is hidden in the widespread anti-inflammatory properties of CBD. 

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CBD prevents inflammation in various ways

One of the factors through which CBD can prevent inflammation is the dysfunction of cytokines, chemicals in the body that mediate inflammation by promoting it.

Endocannabinoids, especially non-psychotic agents such as CBD, affect the cytokine structure and biology of various cellular systems. The anti-proliferative effects of endocannabinoids on cancer cells have been well demonstrated and their effect in eliminating inflammation is significant

CBD to Treat Alzheimer’s and Other Forms of Dementia

Alzheimer’s disease is a disorder that occurs due to the gradual destruction and death of cortical cells and the death of these cells causes dementia in patients.

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Also Read: Medicinal Cannabis And Women’s Health

It can also affect a person’s cognitive abilities.

There is currently no cure for Alzheimer’s disease. But there are certain medications to reduce the symptoms

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Therefore, cannabinoids such as CBD can be effective in fine-tuning vital brain circuits in the nervous system and in treating various types of dementia, including Alzheimer’s.

In this regard, studies were conducted that included a total of 21 cases in which cannabinoids, especially CBD derived from cannabis plants were used as a therapeutic measure against Alzheimer’s disease.

Studies have been performed to investigate the effect of CBD on patients with Alzheimer’s disease on PC12 neurons. The results showed that cannabidiol activates a proxiferous activated receptor through an innate pathway in the central nervous system. When activated, this pathway protects PC12 neurons from oxidative damage and neurotoxicity.

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Also Read: How to Plant Cannabis Seeds Indoors?

Therefore, the results of these studies indicate that CBD can be used as an effective drug to prevent the progression of Alzheimer’s disease. CBD activates the peroxisome activating receptor activator receptor to protect PC12 cells from neurotoxicity and oxidative stress, which ultimately leads to cell death, resulting in indirect cell proliferation with reduced ROS production. 

CBD can also indirectly reduce lipid peroxidation in areas of the central nervous system.

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Over the last 4 years, Vishnu has consistently demonstrated his commitment to writing articles and news pieces. His dedication to the craft is apparent in his continuous contributions, reflecting a passion for delivering informative and engaging content.

Health

IIT-K and BFI collaborate to drive healthcare innovation in India

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IIT-K and BFI forge partnership to accelerate healthcare innovation in India

Kanpur, April 17 (IANS) – The Indian Institute of Technology Kanpur (IIT-K) has entered into a strategic partnership with Blockchain For Impact (BFI) to drive advancements in healthcare in India. Under the BFI-Biome Virtual Network Programme, this collaboration aims to nurture innovations in the healthcare sector.

As part of the partnership, BFI will support IIT Kanpur in promoting entrepreneurial initiatives through the Startup Incubation & Innovation Centre (SIIC). A Memorandum of Understanding (MoU) was signed at IIT Kanpur by Prof. Kantesh Balani, Dean of Resources and Alumni (DoRA), IIT Kanpur; and Dr. Gaurav Singh, CEO BFI.

BFI has committed to allocating over $150,000 across three years to develop programmes tailored to healthcare-focused startups at IIT Kanpur’s SIIC. This collaboration harnesses IIT Kanpur’s expertise in fostering entrepreneurship and BFI’s dedication to advancing biomedical research.

Prof. Kantesh Balani, DoRA, IIT Kanpur, expressed his optimism about the partnership, stating, “This MoU will help us share knowledge, support startups effectively, and improve our capacity-building efforts.” Dr. Gaurav Singh, CEO of BFI, highlighted the inspiring work of IIT Kanpur incubatees in healthcare innovation and the alignment of missions to accelerate impactful solutions in biomedical research.

This partnership signifies a significant step towards advancing healthcare innovation in India by leveraging expertise and resources. The collaboration between IITK and BFI holds promise for improving public health and ensuring equitable healthcare access for all.

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Doctors are hopeful that gene therapy could be a breakthrough for haemophilia, a blood disorder

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Gene therapy holds promise for blood disorder haemophilia: Doctors

On World Haemophilia Day, doctors highlighted the potential of gene therapy in treating haemophilia, a hereditary blood disorder. Haemophilia is caused by missing or defective clotting factors and raises the risk of severe bleeding and joint damage. Genetic counselling and screening are crucial for affected individuals. India has a high number of haemophilia cases, but many go undiagnosed due to lack of screening capabilities.

Gene therapy offers a promising approach to treating haemophilia by delivering functional genes to correct the genetic defect responsible for deficient clotting factor production. Recent clinical trials show positive outcomes, including the use of lentiviral vectors at CMC Vellore. While current treatment involves factor VIII infusions, gene therapy may offer a cure for haemophilia, especially in low and middle-income countries.

According to Anoop P, Sr. Consultant – Haematology at Aster RV Hospital, “Gene therapy is a potentially curative treatment for haemophilia.” It allows for editing the faulty gene of a baby inside the uterus, known to be born with haemophilia due to a family history. Ongoing research on gene therapy shows promising results, indicating a potential paradigm shift in the management and cure of haemophilia.

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The Connection Between Daytime Sleep and Increased Risk of Dementia

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How daytime sleep can raise dementia risk

New Delhi, April 17 (IANS) Compensating for lack of sleep during the daytime may not be as effective as previously thought, warned Dr. Sudhir Kumar, a neurologist based in Hyderabad. According to Dr. Sudhir, daytime sleep is not in sync with the body’s natural clock and can increase the risk of dementia and other psychiatric disorders.

Dr. Sudhir, from Indraprastha Apollo Hospitals, highlighted in a post on X.com that daytime sleep is lighter and does not fulfill the body’s sleep requirements. He explained, “This fact is supported by numerous studies of night shift workers, who are predisposed to stress, obesity, cognitive deficits, and an elevated risk of neurodegenerative diseases.”

The neurologist pointed out that the glymphatic system, responsible for clearing the brain of protein waste products, is most active during sleep. Therefore, when there is a lack of sleep, the glymphatic system may fail, increasing the risk of dementia. Dr. Sudhir stated, “Glymphatic failure is the common pathway of dementia, leading to the accumulation of abnormal proteins in the brain.”

Factors such as poor sleep quality, age, sedentary lifestyle, cardiovascular diseases, obesity, sleep apnoea, circadian misalignment, substance abuse, and depression can also suppress or result in the failure of the glymphatic system. Dr. Sudhir emphasized, “Good sleepers tend to live longer, weigh less, have a reduced incidence of psychiatric disorders, and maintain cognitive function for longer periods.”

In conclusion, Dr. Sudhir advised that consistently sleeping well at night can lead to better cognitive function and decrease the risk of dementia and psychiatric disorders. It is essential to prioritize quality sleep to maintain overall brain health and reduce the risk of neurodegenerative diseases.

–IANS
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