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COVID-19 Testing Explained: How Is It Done & What Is Rapid Antibody Testing?

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To verify for COVID-19 the Reverse Transcription Polymerase or RT-PCR and the Rapid Antibody Check out are utilized. Uncover out what they’re and the way in which it is used.

New Delhi: COVID-19 constructive circumstances have reached over 20,000 in India. The knowledge is simply not absolute as there is a lack of testing kits on the market out there available in the market and inside the nation, which is why testing is usually executed by the use of contact tracing. Contact tracing primarily based on WHO is intently watching the contacts of an contaminated specific individual to hint whether or not or not they have contracted the sickness so that they will get care and remedy if necessary, which is ready to cease extra transmission of the virus. The reason why India has opted for surveillance over mass testing is as a consequence of the shortage of testing kits on the market. There two vital strategies to verify whether or not or not a person has COVID-19- Reverse Transcription Polymerase or RT-PCR and the Rapid Antibody Check out to detect the presence of the virus.

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How does testing work?

There two vital strategies to verify whether or not or not a person has COVID-19. The first being reverse transcription-polymerase chain response or RT-PCR, this verify takes nasopharyngeal swab or sputum sample. This verify can detect as little as one virus particle present in specific individual, nonetheless this verify can solely inform if the specific individual is at current contaminated or not. It cannot inform whether or not or not a person was contaminated earlier and has recovered. The verify outcomes can take wherever between a variety of hours to 2 days. The verify carried out by swab isn’t reliable because of the virus can disappear from the throat and multiply from the lungs. Due to this a sputum verify is much more environment friendly, significantly for a person testing on the second week from publicity.

The second method is through Serology, which takes the blood sample. Immunoglobulin detection assessments are based on the qualitative detection of IgM and IgG which might be significantly generated by the physique in response to SARS-CoV-2 an an infection. IgG antibodies to SARS-CoV-2 sometimes change into detectable 10–14 days after an an infection although they may be detected earlier, and normally peak spherical 28 days after the onset of an an infection. Assays can be carried out in central laboratories (CLT) or by point-of-care testing (PoCT) aka Rapid Antibody Check out. The outcomes can take up to a few minutes to a couple of hours.

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How does Rapid Antibody Check out work?

Rapid Antibody Check out works in an identical technique as a being pregnant verify nonetheless with a blood sample. Accumulate 2-Three drops of current blood/serum or plasma and place it in a sample container and place 2-Three drops of the buffer supplied in the an identical container (cassette). The cassette permits the diluted sample to maneuver by capillary movement. The cassette has SARS-CoV-2 antigen which is able to bind chemically with each IgM or IgG; thus, forming an antigen/antibody complexes of antigen/IgG and/or antigen/IgM and serving to to detect the presence of the virus as a result of it tells us if the physique is combating an an an infection. The verify tools has a administration line, a G line which reveals the presence of IgG (Immunoglobulin), an M line which reveals IgM (Immunoglobulin), and a unfavourable line which is ready to level out if the physique has no antibody. Often all through an an an infection, the physique’s first line of safety is with IgM immunoglobins whereas the IgG is produced later.

In step with an article inside the medical journal The Lancet ‘Antibody assessments are utterly completely different because of they require some data of the proteins that kind the viral coat—significantly, these proteins to which the immune system responds, triggering the manufacturing of antibodies that flag or neutralize the virus.’ Although the Rapid Antibody is simply not as appropriate as RT-PCR, they’re sooner. The PCR assessments work on DNA nonetheless as a result of the coronavirus is an RNA virus it is first reworked to DNA which takes time. That is the explanation Rapid Antibody testing is extraordinarily environment friendly in contact tracing or testing in large volumes as an illustration in hotspots. The ICMR considers this verify as a supplementary verify which will level out the presence of a sickness in a selected house. In step with some research, India continues to be import testing kits and since there is a worldwide demand for these kits India like many nations is working in want of these kits. The ICMR has solely authorised only one homegrown tools, although assessments are being carried out to make testing rather more setting pleasant and quicker.

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Over the last 4 years, Vishnu has consistently demonstrated his commitment to writing articles and news pieces. His dedication to the craft is apparent in his continuous contributions, reflecting a passion for delivering informative and engaging content.

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India News

AstraZeneca’s Covishield To Cause Rare Yet Serious Side Effects

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AstraZeneca's Covishield To Cause Rare Yet Serious Side Effects

A huge update for those who were a part of COVID vaccination programs! Rare side effects of the vaccination have surfaced, questioned by numerous health experts.

The Economic Times reported that AstraZeneca, the British-Swedish multinational pharmaceutical and biotechnology company, has legally acknowledged that its product, Covishield, can cause certain rare side effects.

AstraZeneca developed Covishield, which was produced by the Serum Institute of India. In India, Covishield was one of the primary vaccines provided to citizens.

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AstraZeneca’s Statements

AstraZeneca is currently facing a lawsuit in a UK court. The lawsuit was filed after claims surfaced on the internet that AstraZeneca’s vaccine caused deaths. To date, 51 deaths have been reported, hence 51 cases have been filed against the company.

AstraZeneca finally admitted in one of the court papers that, “Covishield can, in very rare cases, cause TTS.” TTS stands for Thrombosis with Thrombocytopenia Syndrome.

Dr. Rajeev Jayadevan, a medical expert, told ANI,

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“TTS is thrombosis with thrombocytopenia syndrome, which is basically a clot in the blood vessels of the brain or elsewhere, along with a low platelet count. It is known to occur in very rare instances following certain types of vaccines and also from other causes. According to the WHO, adenovirus vector vaccines, in particular, have rarely been associated with this condition.”

TTS: About, Diagnosis, Treatment

TTS, or Thrombosis with Thrombocytopenia Syndrome, is a serious yet rare health condition characterized by low platelet counts (thrombocytopenia) along with the formation of blood clots (thrombosis).

Various symptoms associated with TTS include neurological deficits, shortness of breath, leg swelling, abdominal pain, and severe headaches.

TTS can be diagnosed if blood tests are conducted to assess the levels of platelets in the blood. Moreover, to detect blood clots, imaging studies are required, reported the Times of India.

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TTS can be treated with a multidisciplinary approach. It includes supportive care, anticoagulation therapy to prevent blood clotting, and hospitalization.

To manage and stabilize platelet levels in the body, plasma exchange and intravenous immunoglobulin (IVIG) can also be performed.

Patients with TTS are prone to severe complications like death and organ damage. Hence, close monitoring of patients by healthcare providers is a must.

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Also Read: Online doctor consultations in India increase by 4 times after the Covid-19 pandemic: Report

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Report: Gangster Goldy Brar Is Alive, Confirms US Police

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Report: Sidhu Moosewala Murder Case Prime Suspect, Goldy Brar Is Alive 

The prime suspect in the murder case of a famous Punjabi singer, Goldy Brar, is alive, reported TOI.

Goldy is the infamous Canadian gangster who was earlier rumored to be dead in an alleged incident that took place at Fairmont and Holt Avenue last Tuesday.

In the incident, one of the two individuals reportedly got gunshot wound and succumbed to injuries at the hospital. You can read our story about California shooting incident in which Goldy Brar allegedly got shot here.

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As per the US police, reports of Goldy’s disappearance were circulating all over the internet on Tuesday. However, the U.S. authorities clarified the rumors of Brar’s disappearance in a California shooting incident are untrue. 

The claims were refuted by the Fresno police department and labeled them as fake. William J. Dooley, the Lieutenant, debunked online speculations and announced that the victim of the California shooting was not Goldy Brar. 

William J. Dooley stated,

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“If you are inquiring because of the online chatter claiming that the shooting victim is ‘Goldy Brar’, we can confirm that this is absolutely not true.”

Who is Goldy Brar?

Goldy Brar, hailing from Muktsar Sahib, Punjab, is a close ally of gangster Lawrence Bishnoi. It is anticipated that he is the mastermind behind the assassination of Sidhu Moose Wala, the Punjabi pop icon. 

According to The Economic Times, in January 2024, Satinderjit Singh, also known as Goldy Brar, was designated as a terrorist by the Ministry of Home Affairs under the anti-terror law, UAPA (Unlawful Activities (Prevention) Act). 

Orders by the government-linked Goldy Brar to a listed terrorist organization under the UAPA, Babbar Khalsa International. 

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Goldy Brar has never ceased to vanish from police’s eyes since he murdered Punjabi singer Sidhu Moosewala. His father also was a Police Officer himself.

After completing his graduation and getting a BS degree, he has been operating from Canada remotely. 

Last year Goldy’s statement, targetting Bollywood superstar Salman Khan next made huge media headlines.

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Prajwal Revanna ‘Sexual Abuse’ Viral Video Case: Here’s What We Know So Far

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Prajwal Revanna

The viral sex video case involving Prajwal Revanna, a member of the prominent Karnataka political family JDS, has created a storm in the Karnataka political scene.

The video, which involves a trail of deceit connected to a 16-acre ancestral property, has led to allegations of intimidation and blackmail, resulting in legal action and widespread dissemination of the tapes.

The central figure, now-suspended MP Prajwal Revanna, is the grandson of former Prime Minister HD Deve Gowda.

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The origins of this scandal trace back to an acrimonious land dispute within the inner echelons of H D Deve Gowda’s son, H D Revanna’s family. In 2023, a trusted lieutenant of the Revanna family, Kartik, went rogue and decided to challenge the family’s monopoly.

At the center of the controversy was a 16-acre piece of land located in the ancestral village of the Deve Gowda clan in Holenarsipura.

This land soon became a prestige issue and the bone of contention between Kartik and the Revanna family.

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Tensions escalated when Kartik, feeling marginalized, lodged a complaint in December 2023 accusing Prajwal and his mother of using coercive means to hand over the land.

This was followed by a series of revelations about clandestine activities within the Deve Gowda lineage.

It was also revealed that Kartik had access to Prajwal’s mobile phone, with which he recorded the incriminating videos.

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The scandalous videos were initially shared on his personal device and later used as a tool of blackmail after Kartik’s fallout with the family.

Kartik later approached prominent lawyer and BJP functionary G Devaraj Gowda, which further aggravated the situation.

This led the Revanna family to seek legal action against some media outlets and individuals, alleging a smear campaign against them.

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The courts ruled to forbid the release of the videos in any manner.

G Devarajegowda maintained silence and did not release the videos, citing concerns for privacy and dignity.

However, his political rivals did not let the opportunity slip and started a widespread dissemination of the tapes ahead of the elections.

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According to Kartik, he doesn’t know what Devaraj did with the videos.

Whenever he asked about them, Devaraj told him to wait.

It is also said that Devaraj gave the videos to the BJP high command and even asked the party not to give a ticket to Prajwal, and wrote a letter to this effect.

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Later, Kartik asked Devaraj to return the pen drive containing the videos.

Devaraj gave him a copy of the letter he had written to the BJP high command, stating that even if he did not get justice from the court, he would seek it in this way.

Later, Kartik said that Devaraj discussed the matter with the media and started ignoring him.

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Devaraj also stated to the media that he had given some copies of the videos to some friends from Congress, but this has been outrightly denied by Kartik, who added that Devaraj had cheated him.

The Karnataka Government has initiated a special probe and has formed an SIT team to investigate the matter.

Things have become even more complicated after Prajwal’s departure for Frankfurt, Germany, just a day before the formation of the SIT, leading to many unanswered questions.

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The SIT team has been tasked with investigating allegations of sexual harassment and an alleged obscene video scandal against Prajwal Revanna, the current Member of Parliament (MP) representing the Janata Dal (Secular) from Hassan.

It is not clear how many women have been victims in this high-profile sex scandal. It is alleged that a number of women were sexually harassed, and videos were made.

More than 3000 videos have gone viral on different social media platforms like Twitter, Reddit and more.

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The videos started surfacing about 5 days before the start of the second phase of the voting for the Lok Sabha 2024 elections, which occurred on 20 April.

Voting for the second phase of the elections happened on 26 April in different parts of the country, including 14 Lok Sabha seats in Karnataka.

Prajwal Revanna, however, remained unfazed and even participated in the election campaigns, asking voters to support the NDA alliance, of which JD(S) is a component.

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Post-elections, he took a flight to Germany, and opposition parties have alleged that he fled the country to escape prosecution.

Amidst these developments, a woman who had worked with the Revanna family filed an FIR and made many shocking charges against both HD Revanna and Prajwal Revanna.

The woman stated that she first came in contact with the Revanna family when she was employed as a worker during their son Sooraj’s marriage.

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Later, Prajwal Revanna would often call her alone to a room.

She revealed that six women used to work for the Revanna family and all were petrified and afraid of Prajwal Revanna.

The woman also alleged that whenever the female members of the Revanna family were out, Prajwal Revanna would call her and behave in an objectionable manner.

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She also accused him of sexually molesting her.

The Holanarsipur Police have since recorded the statement of the woman and are investigating the matter, and have registered a case against both H D Revanna and Prajwal Revanna.

Also Read: Dhruv Rathee Debunked Viral Claims Of Him and His Wife Being Pakistani

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